Aquatox Research offers chemical toxicity testing services with freshwater organisms in addition to the specialized toxicity testing and chemical testing (Microtox) and information-based services highlighted elsewhere in this website. Tests are typically conducted with larval fathead minnows (Pimephales promelas) and early instar invertebrates, such as Ceriodaphnia dubia.

A standardized approach to aquatic toxicity testing of chemicals begins with a preliminary screening test to define the toxic range using an order of magnitude dilution series (e.g. 1, 10, 100 and 1,000 mg/L or ppm). The subsequent definitive test employs a narrower range of treatment concentrations (typically 50% or greater) in order to generate a median lethal concentration (LC50) in acute, short-term tests. Both acute screening and definitive tests are required in the event chronic toxicity data are requested. Each test in sequence provides valuable information to best design subsequent tests and minimize repeat tests due to excessively low or high dilution series not bracketing the targeted endpoint.

Aquatox Research routinely conducts tests with fathead minnows and invertebrates and maintains an active reference testing program to demonstrate quality assurance. Aquatox Research staff possesses more than 30 years of experience in conducting tests with fathead minnows and invertebrates.